Background: Platelets have an active role in haemostasis and are used in patients mainly to stop or prevent life-threatening bleeding. The blood components transfused commonly are packed red blood cells followed by platelets. One of the objectives of the World Health Organization is to promote the availability and safety of blood by targeting blood donors in certain environments.
Objective: To study the socio-demographic, and haematologic profiles including platelet loss and intention to repeat platelet donations
Materials and Methods: This retrospective observational cross-sectional study includes data from 503 plateletpheresis male donors picked in a simple random method. The details such as socio-demographic, anthropometric, vitals, haematologic parameters, and type of apheresis instrument used were collected and analysed. Platelet loss was compared. 109 were first-time donors and 394 were repeat donors.
Results: Haemoglobin in first-time donors was (15.08 g/dl) and in repeat donors was (14.744 g/dl). BMI was 26.360 in repeat donors and 25.501 in first-time donors. Neutrophil/ lymphocyte, lymphocyte/ monocyte, and platelet/ lymphocyte ratios were 2.41 ± 1.19, 4.08 ± 2.16, and 153.98 ± 62.93 respectively. The platelet loss in first-time donors was (75.697 ± 21.809) x 1 3 /μl and in repeat donors, it was (74.444 ± 26.529) x 10
3 /μl; was significantly more with MCS+ (75.249 ± 20.306) x 10 3 /μl (SDP), 148.000 ± 17.776 x 10 3 /μl (DDP) compared to SPECTRA OPTIA 53.667 ± 11.949 x 10 3 /μl (SDP) 94.876 ± 21.067 x 10 3 /μl (DDP) and TRIMA ACCEL 52.285 ± 16.362 x 10 3 /μl (SDP), 103.673 ± 24.736 x 10 3 /μl (DDP). The number of voluntary donors (68.49%) associated with the intention to repeat platelet donation was higher compared to replacement donors (53.91%).
Conclusion: First-time donors can safely undergo plateletpheresis. NLR, PLR, and LMR can be established for the Indian population with the help of a platelet registry